The BIOMEC Lab participated in the 27th Congress of the European Society of Biomechanics, which was held in Porto (Portugal) from the 26th to the 29th of June 2022. Míriam Febrer presented a study done in collaboration with the Laboratory for Movement Biomechanics at ETH Zürich (Switzerland). The main goal of this work was to apply musculoskeletal simulations of full body and joint level mechanics to establish realistic boundary conditions for future computational investigations of total knee replacement wear. Particularly inspiring were the keynote lectures given by Prof. Amir A. Zadpoor, about meta-biomaterials, and by Prof. Massimo Sartori, about modelling the neuromuscular system for human-robot interfacing. The beautiful conference venue (Alfandega Porto Congress Centre), by the Duero river, facilitated interesting discussions during coffee and lunch breaks.